p53 antibody

Catalog No. ABIN2734034

The Mouse Monoclonal anti-p53 antibody has been validated for WB, IHC, IF and FACS. It is suitable to detect p53 in samples from Human. There is 1 publication available.

Quick Overview for p53 antibody (ABIN2734034)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This p53 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3D5

Product Details anti-p53 Antibody

Characteristics: Homo sapiens tumor protein p53 (TP53), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human TP53 (NP_000537) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

References for anti-p53 antibody (ABIN2734034)

Shi, Liu, Zhang, Geng, He, Nu, Pang: "Decreased sirtuin 4 expression is associated with poor prognosis in patients with invasive breast cancer." in: Oncology letters, Vol. 12, Issue 4, pp. 2606-2612, (2016) (PubMed).

Target Details for p53

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name: TP53

Molecular Weight: 43.5 kDa

Gene ID: 7157

NCBI Accession: NM_000546

HGNC: 7157

Pathways: p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect